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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
17.27
Human Site:
Y143
Identified Species:
31.67
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
Y143
H
A
E
S
E
Q
E
Y
E
E
E
Q
E
P
P
Chimpanzee
Pan troglodytes
XP_508321
684
75407
Y143
H
A
E
S
E
Q
E
Y
E
E
E
Q
E
P
P
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
Y143
H
A
E
S
E
Q
E
Y
E
E
E
Q
E
P
P
Dog
Lupus familis
XP_534086
793
86791
Y261
Q
A
E
S
E
Q
E
Y
E
E
E
Q
E
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
E143
A
E
L
D
Q
D
Y
E
E
E
Q
E
P
P
K
Rat
Rattus norvegicus
XP_002725626
681
74519
Y142
Q
A
D
L
D
Q
D
Y
E
E
E
Q
E
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
E106
E
E
K
R
K
K
E
E
L
V
A
K
R
I
E
Chicken
Gallus gallus
XP_421015
633
66869
C112
P
K
K
R
R
R
T
C
E
N
V
S
Q
A
P
Frog
Xenopus laevis
Q6NU13
800
83727
E148
Q
S
E
S
E
R
E
E
E
Q
E
E
M
P
P
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
K111
Q
P
K
K
R
Q
S
K
G
S
S
T
E
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
K80
L
L
A
K
R
D
E
K
S
K
N
K
I
R
K
Honey Bee
Apis mellifera
XP_395689
579
67372
Q78
A
L
R
D
H
K
A
Q
S
R
I
N
K
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
K109
R
S
K
P
K
P
T
K
K
P
A
A
K
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
100
93.3
N.A.
20
66.6
N.A.
6.6
13.3
53.3
13.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
40
86.6
N.A.
33.3
33.3
80
20
N.A.
20
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
39
8
0
0
0
8
0
0
0
16
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
16
8
16
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
16
39
0
39
0
54
24
62
47
47
16
47
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
24
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% I
% Lys:
0
8
31
16
16
16
0
24
8
8
0
16
16
8
16
% K
% Leu:
8
16
8
8
0
0
0
0
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% N
% Pro:
8
8
0
8
0
8
0
0
0
8
0
0
8
54
62
% P
% Gln:
31
0
0
0
8
47
0
8
0
8
8
39
8
0
8
% Q
% Arg:
8
0
8
16
24
16
0
0
0
8
0
0
8
8
0
% R
% Ser:
0
16
0
39
0
0
8
0
16
8
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _